DiabetesPro SmartBrief
Lilly: Orforglipron outperforms semaglutide in trial | Medtronic shares 3-year data for MiniMed 780
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September 17, 2025
 
 
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Diabetes In Focus
 
How bariatric surgery compares with GLP-1s
 
Closeup of preparation for a gastric bypass.
(Ahmet Rauf Ozkul/Getty Images)
A study in the journal Nature Medicine found that metabolic surgery may offer long-term health benefits, including lower risk of death, compared with GLP-1 agonists in patients with obesity and diabetes. Bariatric surgery was associated with a 32% lower risk of death, a 47% lower risk of nephropathy and a 35% lower risk of major adverse cardiovascular events. "Surgery should not be reserved as a last resort," said researcher Dr. Ali Aminian.
Full Story: Healio (free registration) (9/17)
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On October 2 at 1 PM EST, discover how to link data across platforms and tackle governance challenges. Learn from Baylor Scott & White's digital and analytics leaders in this webinar to find out how they replaced IBM initiate and built a phased Customer 360 to unify 46M identities across Epic, Snowflake, and JV Systems.
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Nutrition & Wellness
 
Study links food insecurity to eating disorders in US
Low-income individuals show a higher prevalence of eating disorders, challenging the stereotype that these disorders affect only the affluent, according to a study in JAMA Network Open. The research notes that food insecurity can lead to unhealthy eating patterns and mental health issues, and experts warn that recent cuts to nutrition programs could exacerbate the situation.
Full Story: CNN (9/17)
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Study examines link between food texture, overeating
 
Pile of potato chips
(Chris Clor/Getty Images)
Researchers in the Netherlands are examining the impact of altering the texture of ultra-processed foods on energy intake. The study, published in Nutrition Bulletin, involves two 14-day diet phases during which participants consume hard-textured and soft-textured ultra-processed foods in random order to assess changes in energy intake and metabolic outcomes.
Full Story: News Medical (9/16)
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Study: Blueberries enhance immune response in infants
 
blueberries
(Pixabay)
Introducing blueberries as one of an infant's first solid foods may enhance immune function and gut health, according to a study published in Frontiers in Nutrition. The research shows that infants consuming freeze-dried blueberry powder experience improved allergy symptoms, reduced inflammation and beneficial changes in gut microbiota.
Full Story: Newsweek (tiered subscription model) (9/16)
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Sales Reimagined: Delivering Real Impact
AI is changing sales. Join leaders from BCG, Slack, Salesforce, and Workday on Oct. 7 at 3PM EST for a fireside chat on how to navigate the agentic era and reshape your sales teams for the future. Discover how to embed AI across the sales experience and lead hybrid teams of human talent augmented by digital agents. Register now to learn how to drive tangible impact and prepare your sales organization for what's next.
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Practice Update
 
Lilly: Orforglipron outperforms semaglutide in trial
Eli Lilly and Co. said its orforglipron outperformed oral semaglutide in reducing A1C and weight in patients with type 2 diabetes, according to top-line results from the ACHIEVE-3 trial. Lilly plans to seek regulatory approval in 2026.
Full Story: Healio (free registration) (9/17)
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Lilly, Novo gear up for oral obesity drug launches
Eli Lilly and Co. and Novo Nordisk are set to introduce oral obesity drugs in the US next year pending regulatory approval. These daily pills are expected to broaden the use of GLP-1 medications being administered as weekly injections.
Full Story: CNBC (9/12)
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Medtronic shares 3-year data for MiniMed 780G
Medtronic reported three-year real-world data showing improved glycemic control with the MiniMed 780G automated insulin delivery system. The findings, presented at the European Association for the Study of Diabetes meeting in Vienna, showed a rise in time-in-range for patients with Type 1 diabetes, reaching 78.6% and remaining stable over 36 months.
Full Story: Drug Delivery Business News (9/16)
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Eliminate Operational Blind Spots
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ICYMI: The Most Popular Stories From Our Last Issue
 
 
Hypoglycemia may raise risk of diabetic retinopathy
Medscape (9/16)
 
 
Type 2 diabetes tied to doubled risk of sepsis
Medscape (9/16)
 
 
 
 
Trends & Technology
 
FDA targets ads for lower-case obesity drugs
The FDA has issued 40 untitled letters and 100 cease-and-desist notices to drugmakers and telehealth companies, saying their advertisements are misleading or deceptive. Among the companies that received letters were Hims & Hers, which markets compounded weight-loss drugs.
Full Story: The Associated Press (9/16), Fierce Pharma (9/16)
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