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| News and resources for diagnostics and laboratory medicine professionals | SIGN UP ⋅ SHARE |
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The newly discovered long non-coding RNA molecule FAM151B-DT may regulate protein homeostasis in the brain. The researchers found that silencing FAM151B-DT led to increased aggregation of tau and α-synuclein, which are proteins associated with neurodegenerative diseases.
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A Phase 1 trial of the CRISPR-Cas9 gene therapy nexiguran ziclumeran showed an 87% reduction in serum transthyretin levels over three years for patients with transthyretin amyloid cardiomyopathy.
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A study found that the protein FGD3 could serve as a predictive biomarker for breast cancer treatment efficacy. Researchers found a strong correlation between FGD3 levels and patient responses to chemotherapy.
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AI isn't hype anymore—it's here. Join EPAM, Stripe, and commercetools to learn how to harness AI—responsibly and effectively. See how AI is reshaping the shopper journey, and learn why composability is key to doing it right. The brands moving first are already winning. Register now!
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An XGBoost algorithm to predict urine culture outcomes demonstrated robust performance, with an AUROC of 0.834 during internal validation and 0.800 in external validation, supporting its potential application in clinical settings.
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Researchers have identified death-associated protein kinase 1 as a novel biomarker for liver metastasis in colorectal cancer. The study, which used machine learning and multiomics approaches, found that DAPK1 is upregulated in metastatic tissues and associated with macrophage infiltration.
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Drexel's online MS in Drug Discovery and Development program gives you a unique, career-focused opportunity to evaluate and engage with the entire drug discovery process. You'll learn from the best, with the best – surrounded by leaders in the pharmaceutical and biotechnology industries. Learn more today.
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A report in the journal Science Translational Medicine details how AI can improve the diagnosis of blood cancers by automating the analysis of bone marrow smears. The researchers trained deep learning models to quickly and accurately classify cells.
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Retailers face labor shortages, rising customer expectations and unpredictable supply chains, which drive them to reinvent their operations. With mobile technology, retailers can provide real-time visibility, contactless payments, digital receipts and loyalty programs. This paper explores how mobile solutions transform retail operations and engage consumers.
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Hologic's Genius digital diagnostics system has received expanded CE marking in the EU, allowing it to image and review both cell and tissue specimens. Previously approved for cell analysis, the system can now perform whole slide imaging.
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The FDA has approved Kura Oncology and Kyowa Kirin's once-daily oral treatment Komzifti for patients with acute myeloid leukemia with an NPM1 mutation, which occurs in about 30% of cases.
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The FDA has introduced the "plausible mechanism pathway" to accelerate the development and approval of bespoke gene editing therapies. The pathway, detailed in the New England Journal of Medicine, aims to extend the success of single-patient treatments to a broader regulatory framework.
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