A comparison study involving 60 patients, published in The Journal of Nuclear Medicine, found [68Ga]Ga-AZ-093 and [68Ga]Ga-AZ-NI-093 are promising radiopharmaceuticals for prostate cancer. Researchers said larger studies are needed to determine the clinical value of the radiopharmaceuticals.

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A technical report in Cureus highlights potential quantification errors in amyloid PET imaging when using the Centiloid scale. The report describes a case where significant cortical amyloid was visually apparent, but the Centiloid value was underestimated, leading to a false-negative result. This discrepancy was attributed to the use of the whole cerebellum as a reference region, which may lower standardized uptake value ratios compared with cerebellar gray matter.

A study published in the journal European Urology looked at the overall survival rate for 1,889 patients with prostate cancer who had PSMA PET for initial staging, as an evaluation of PRIMARY score, which was implemented in Prostate Cancer Molecular Imaging Standardized Evaluation version 2. A PRIMARY score of 5 was linked to shorter OS but researchers noted additional prognostic value was seen by adding PI-RADS or clinical T stage to the analysis.

Researchers studied the potential of photon-counting CT for T3-T4 rectal cancer staging, finding an AUC range of 80% to 86%, compared with 78% to 88% with MRI. "PCD CT is particularly advantageous for patients with contraindications to MRI because it can provide a practical and efficient imaging alternative," the study authors wrote in a radiology journal. "Furthermore, PCD CT offers an adjunctive modality to MRI, especially when MRI has artifacts."

GE HealthCare has agreed to acquire Intelerad, an imaging software provider, for $2.3 billion in cash. The acquisition is expected to enhance GE HealthCare's portfolio with cloud-enabled and AI-powered solutions, expanding capabilities in radiology and cardiology across outpatient networks.

A record 47% of Americans are anxious about affording health care in 2026, marking the highest level since tracking began in 2021, according to a West Health-Gallup survey. The survey, based on about 20,000 adults across the US, highlighted concerns about prescription drug costs, with 15% of adults saying prescription costs cause significant stress.

The future of enhanced Affordable Care Act subsidies is uncertain as Congress faces a year-end deadline. Republicans are divided on how to proceed, with some proposing Health Savings Accounts as an alternative, while others support a one-year extension. Without action, 22 million people in the US could see health insurance premiums increase when the subsidies expire Dec. 31.

The White House is preparing an executive order to block state-level AI laws, aiming to establish a federal standard for AI model reporting and disclosure. This move, supported by tech lobbyists, seeks to prevent a patchwork of state regulations that could complicate compliance. However, it faces opposition from state legislators and legal experts who argue that states have the right to regulate technology within their borders.