Endpoints News
Endpoints wins three Neal Awards Read in browser
Endpoints News
Thank you for reading, dupa dupackia!
basic
UPGRADE
M T W Thu F
23 April, 2026
sponsored by Thermo FIsher Scientific
Flexibility in drug development: From tactical response to strategic discipline
This whitepaper examines how flexibility in drug development shows up in practice across development, manufacturing, and clinical supply, drawing on execution and experience across Thermo Fisher Scientific Pharma Services. Read the whitepaper to explore how flexible development and manufacturing systems help drug programs adapt to changing requirements while maintaining control and reliability.
Get the white paper now
presented by Clinical Enrollment
This Founder Could­n't Find His Own Clin­i­cal Tri­al. Now He's En­rolling Hun­dreds of Pa­tients for Phar­ma's Biggest Names
spotlight
top stories
1. David Reese to retire from Amgen
2.
news briefing
Novo's pill for kids; Altimmune’s $225M offering; Merck teams with Google Cloud
3. Updated: Roche says its investigational breast cancer pill could outsell Herceptin
4. Updated: Sanofi defends Garijo appointment, says it is 'fully committed' to immunology
5. Exclusive: Gravity Rail raises $2.75M for customizable AI to communicate with patients
6. OpenAI's head of health lays out the AI giant’s healthcare ambitions
7. AbbVie's $1.4B North Carolina manufacturing site to finish during Trump's term
more stories
 
Karen Weintraub
.

Longtime Amgen exec David Reese will retire at the end of June. Currently the inaugural chief technology officer, Reese has been in the company’s leadership since 2005. Lei Lei Wu has the details here.

.
Karen Weintraub
Deputy Editor, Endpoints News
David Reese (Amgen via website)
1
by Lei Lei Wu

Long­time Am­gen leader David Reese is re­tir­ing at the end of June, Am­gen an­nounced Wednes­day evening.

Reese, 63, cur­rent­ly serves as chief tech­nol­o­gy of­fi­cer, a role he cre­at­ed at Am­gen in 2023. Since then, he has led the com­pa­ny’s adop­tion of AI, es­pe­cial­ly as a key part of drug de­vel­op­ment.

Be­fore his time as chief tech­nol­o­gy of­fi­cer, Reese was head of R&D be­gin­ning in 2018. He joined Am­gen in 2005 as a clin­i­cal de­vel­op­ment leader in on­col­o­gy.

Reese told End­points News in 2025 that when he pitched the chief tech­nol­o­gy role, he be­lieved it was "the hinge mo­ment" for AI.

"Dave rec­og­nized ear­ly the im­pact that ad­vances in bi­ol­o­gy and tech­nol­o­gy would have on our in­dus­try and helped lead Am­gen through that shift," Am­gen CEO Bob Brad­way said in a press state­ment.

Click here to continue reading
News Briefing: Quick hits from the biopharma web
2
by ENDPOINTS

No­vo Nordisk’s GLP-1 pill works in kids with di­a­betes: Type 2 di­a­betes pa­tients aged 10 to 17 who took Ry­bel­sus for about six months had a sta­tis­ti­cal­ly sig­nif­i­cant 0.83% cut in their blood sug­ar lev­els com­pared with place­bo, No­vo said Thurs­day. The com­pa­ny plans to sub­mit the Phase 3a da­ta to reg­u­la­tors in pur­suit of a la­bel ex­pan­sion in this new pop­u­la­tion. — Eliz­a­beth Cairns

Al­tim­mune’s $225M of­fer­ing: The Mary­land biotech priced its pub­lic of­fer­ing on Wednes­day night to help bankroll its up­com­ing Phase 3 in MASH. The com­pa­ny’s stock price ALT was down 17% in pre-mar­ket trad­ing on Thurs­day. — Kyle LaHu­cik

Mer­ck teams with Google Cloud: The New Jer­sey drug gi­ant will work with the tech be­he­moth to bol­ster its “dig­i­tal back­bone” via a mul­ti-year in­vest­ment “val­ued at up to $1 bil­lion.” The phar­ma said the al­liance will dig­i­tize da­ta and “help boost pro­duc­tiv­i­ty” among the com­pa­ny’s 75,000 glob­al em­ploy­ees. — Kyle LaHu­cik

Click here to continue reading
TOP R&D TRENDS IN 2026:
The R&D 15 is John Carroll’s annual reckoning with where biopharma’s biggest players are really investing — and where they’re not. This year he’s back at the table with some of the industry’s top research chiefs for a frank, one-hour conversation on the trends shaping drug development in 2026 and beyond. Join us.
3
by Elizabeth Cairns

Roche still has high sales hopes for its breast can­cer pill giredestrant de­spite the drug’s fail­ure in a first-line tri­al ear­li­er this year.

CEO Thomas Schi­neck­er said Thurs­day that the drug could reach three times as many pa­tients as Roche's breast can­cer block­buster Her­ceptin, which at its peak in 2018 had sales of about $7 bil­lion.

Giredestrant is await­ing ap­proval in the US as a sec­ond-line ther­a­py for cer­tain metasta­t­ic breast can­cer pa­tients, with an ini­tial de­ci­sion due in De­cem­ber. Roche has al­so just sub­mit­ted it for ap­proval for use af­ter surgery in cer­tain pa­tients with ear­ly breast can­cer. The com­pa­ny used a pri­or­i­ty re­view vouch­er for this fil­ing, which could mean an­oth­er ap­proval will al­so come this year.

Click here to continue reading
4