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iECURE learns that repeating a miracle isn't easy Read in browser
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13 May, 2026
US Pharma and Biotech Summit - May 14, 2026
Policy shifts, regulatory unknowns, and a dealmaking environment that won’t sit still — US biopharma is navigating serious uncertainty. Join FT Live and Endpoints News for the conversations that will define what comes next.
presented by Premier, Inc.
Ex­ec­u­tive Brief: How to Fu­ture-Proof and Dif­fer­en­ti­ate Your Busi­ness with RWD/RWE
top stories
1. After an apparent cure, a gene editing company struggles to repeat the magic
2. Takeda to target 4,500 jobs as incoming CEO continues restructuring
3. Valneva to cut up to 15% of jobs as reduced travel hits vaccine demand
4. Post-Hoc: What brought down the FDA commissioner 
5. Behind Galapagos’ transformation into Lakefront Biotherapeutics
6. Lilly points to low-dose Zepbound and Foundayo as weight loss maintenance options
7. Merck KGaA's clients are stockpiling due to Iran war, supporting guidance boost
more stories
 
Lydia Ramsey Pflanzer
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Hi from the sky! I'm en route to NYC for the Financial Times US Pharma and Biotech Summit, held in partnership with Endpoints. Catch me onstage tomorrow with Drew Armstrong and Max Bayer to talk about FDA Commissioner Marty Makary's resignation, and what's next for the agency.

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Lydia Ramsey Pflanzer
Deputy Editor, Endpoints News
Jim Wilson, iECURE scientific advisor (Credit: GEMMABio)
1
by Ryan Cross

BOSTON — Ear­ly last year, start­up iECURE’s ex­per­i­men­tal gene ther­a­py seem­ing­ly cured a ba­by of a life-threat­en­ing ge­net­ic dis­ease.

But new re­sults test­ing the same...

Read full story
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by Nicole DeFeudis

Take­da will cut rough­ly 9% of its work­force over the next fis­cal year as the next CEO puts her stamp on a years­long re­struc­tur­ing.

About...

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3
by Kyle LaHucik

French vac­cine mak­er Val­ne­va is lay­ing off 10% to 15% of its work­force and re­duc­ing rev­enue pro­jec­tions due to "an emerg­ing ad­verse trend in trav­el...

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LGBTQ+ LEADERSHIP IN 2026
LGBTQ+ diversity drives innovation in biopharma — but transgender and non-binary professionals face rising challenges. Endpoints is going live with our fourth annual special report celebrating the honorees giving voice and visibility while forging ahead across life sciences. Join us.
Former FDA Commissioner Marty Makary at his Senate confirmation hearing in Washington in 2025 (Bill Clark/CQ Roll Call via AP Images)
4
by Drew Armstrong

Mar­ty Makary nev­er stood a chance.

Over the last few days, the now-for­mer FDA com­mis­sion­er had been left to twist in the wind, af­ter head­lines...

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5
by Kyle LaHucik

CHICA­GO — From a 22nd-floor of­fice over­look­ing the Chica­go River­walk, in the heart of the Mid­west hub’s white-col­lar down­town dis­trict, Lake­front Bio­ther­a­peu­tics’ ex­ec­u­tives hope to...

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