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top stories
1. Updated: Biogen won’t be ‘impulsive’ with anti-tau Alzheimer’s drug
2. AstraZeneca follows Merck with Phase 3 win in bladder cancer
3.
news briefing
A Series A, B and an IPO; Cabaletta reports CAR-T results
4. Updated: BeOne’s next-gen BCL2 inhibitor wins FDA approval, taking aim at Venclexta
5. Regenxbio's Duchenne study succeeded. Will it be enough to convince the FDA?
6. After an apparent cure, a gene editing company struggles to repeat the magic
7. Takeda to target 4,500 jobs as incoming CEO continues restructuring
more stories
 
Alex Hoffman
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Biogen thinks it has another Alzheimer's contender, and although BIIB080 missed the mark in Phase 2, it's full steam ahead with pivotal studies — kind of. “We don’t want to be too impulsive about moving to Phase 3,” Biogen's Priya Singhal told Max Gelman. Read more from Max here.

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Alex Hoffman
Senior Copy Editor, Endpoints News
1
by Max Gelman

Here we go again?

Bio­gen re­port­ed heav­i­ly an­tic­i­pat­ed Alzheimer’s da­ta, say­ing its tau-tar­get­ing drug BI­IB080 missed its pri­ma­ry end­point in a Phase 2 study but...

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2
by Elizabeth Cairns

A com­bi­na­tion of As­traZeneca's Imfinzi with Pfiz­er and Astel­las’ Pad­cev kept more blad­der can­cer pa­tients alive than stan­dard of care, the com­pa­ny said Thurs­day.

As­traZeneca...

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News Briefing: Quick hits from the biopharma web
3
by ENDPOINTS

💸 A Se­ries A ex­ten­sion: US-Chi­na biotech De­gron Ther­a­peu­tics has col­lect­ed an ad­di­tion­al $40 mil­lionfor its mol­e­c­u­lar glue de­grad­er plat­form. The San Diego and...

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4
by Ayisha Sharma

BeOne Med­i­cines has clinched US ac­cel­er­at­ed ap­proval for its drug son­ro­to­clax in man­tle cell lym­phoma (MCL), mark­ing the start of its bid to chal­lenge Ab­b­Vie...

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Regenxbio CEO Curran Simpson at Endpoints' #JPM26 event (Brian Benton Photography)
5
by Lei Lei Wu

Re­genxbio said Thurs­day that its Duchenne mus­cu­lar dy­s­tro­phy gene ther­a­py met the bar in a piv­otal study, and it’s aim­ing for FDA ap­proval in 2027...

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