politics
House Republicans say DEI is back?
The Trump administration spent much of 2025 systematically purging any hint of diversity, equity, and inclusion from the government. Now, the Republican-controlled House wants the FDA to put a little DEI back into its work, my colleague John Wilkerson reports from D.C.
A recent FDA funding bill includes a report setting expectations for how the money will be used. The report encourages the agency to require study sponsors “to submit a diversity action plan for phase 3 studies of new drugs.” Under the Biden administration, the FDA pushed for the inclusion of more women and people of color in clinical trials, and published draft guidance on the matter. Trump officials swiftly canned the whole endeavor. Could the FDA dip a toe back in? And what does “DEI” mean to Republicans now? Read more from John.
consumer safety
Legitketaminesuppliers dot com is actually … not legit, FDA says
The FDA scolded a bunch of online ketamine retailers this week. The agency posted 14 letters to companies with names like “Legit Ketamine Suppliers” and “Ket Plug,” telling them to stop selling unapproved ketamine products. Injectable ketamine drug products come with significant risks, which are not disclosed to consumers, the FDA said. It’s especially risky if ketamine is provided without medical supervision.
FDA approved ketamine for use as a surgical anesthetic back in the 1970s. In 2019, the agency approved Johnson & Johnson's Spravato, an esketamine nasal spray, for treatment-resistant depression in adults (it was later OK’d as a standalone depression treatment). Many in the behavioral health space have been cautiously optimistic about ketamine, even as the drug takes on a life of its own at infusion clinics that advertise to people with serious mental health conditions. — Lizzy Lawrence
first opinion
Where do AI chatbots fit into dementia care?
Artificial intelligence-driven chatbots trigger mixed feelings for many. They can be convenient helpers on a wide range of tasks, or low-maintenance collaborators. But chatbots can also lead vulnerable people into psychosis or worse in rare cases. For people with dementia and their family members, AI chatbots, thoughtfully used, could offer a reprieve, medical ethicist Jason Karlawish writes in First Opinion.
For people with diseases such as Alzheimer’s, easy-to-use tech can make up for impairments that complicate daily living (think: meal planning, paperwork, bills). AI agents can remind users of important tasks or even automate them — work typically done by human caregivers. But chatbots can also offer something more: endless personal conversation.
The “feeling of dignity in the face of dementia is the north star against which these many promising technologies ought to be judged,” Karlawish writes.