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top stories
1. Amylin design debate heats up as Lilly's crucial mid-stage weight loss data near
2. Merck, Moderna declare Phase 3 success for personalized mRNA cancer vaccine
3. Bristol Myers' China partner says bispecific ADC clears fourth cancer trial, this time in NSCLC
4. The most interesting takeaway from Anthropic’s design study has nothing to do with proteins
5.
news briefing
Amgen cans its TScan partnership; Amylyx reveals $350M offering
6. Federal appeals court revives part of Teva's IRA case as Austedo price cuts loom
7. Trump to pick Heidi Overton to lead the FDA following a run of volatile leadership
more stories
 
Karen Weintraub
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Eli Lilly has a crucial readout coming on a new drug that mimics amylin, and expectations are high. Elizabeth Cairns describes the different classes of these drugs — and why focusing on one receptor may produce better results.

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Karen Weintraub
Deputy Editor, Endpoints News
1
by Elizabeth Cairns

In the amylin race, drug de­sign ap­pears to be a key dif­fer­en­tia­tor.

Lat­er this year, No­vo Nordisk’s Ca­griSe­ma is like­ly to be­come the first ap­proved drug...

Read the full story
2
by Max Gelman

The next gen­er­a­tion of im­munother­a­py ap­pears to have ar­rived.

Mer­ck and Mod­er­na on Wednes­day said their per­son­al­ized can­cer vac­cine, known as in­tismer­an au­to­gene, suc­ceed­ed in...

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3
by Ayisha Sharma

Chi­nese biotech Biokin said its EGFRx­HER3 bis­pe­cif­ic an­ti­body-drug con­ju­gate passed a late-stage Chi­na tri­al in a ge­net­i­cal­ly-de­fined form of lung can­cer, buoy­ing op­ti­mism for a...

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Dario Amodei, co-founder and CEO of Anthropic (Jason Henry/Bloomberg via Getty Images)
4
by Andrew Dunn

An­throp­ic’s AI sys­tem Claude over­saw a re­search cam­paign that de­signed and gen­er­at­ed minipro­teins from scratch, the AI lab said in a Tues­day blog post...

Read the full story
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