Oncology (Cancer) / Hematologic Malignancies Update

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FDA approves lirafugratinib for previously treated, unresectable, locally advanced or metastatic cholangiocarcinoma

On September 23, 2026, the Food and Drug Administration approved lirafugratinib (Lyrfigtu, Elevar Therapeutics, Inc.), a kinase inhibitor, for the treatment of adults with previously treated unresectable, locally advanced or metastatic cholangiocarcinoma harboring a fibroblast growth factor receptor 2 (FGFR2) gene fusion or other rearrangement.


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