FDA databases that physicians and public health experts rely on for key drug safety and manufacturing information have been neglected due to DOGE-directed layoffs, leaving health professionals flying blind on basic questions about certain drugs they're prescribing, current and former FDA officials tell Axios. Why it matters: Information gaps that have become a hallmark of the workforce reductions and Kennedy's sweeping reorganization of federal health agencies are putting patient safety at risk, according to agency employees. "It's really a nightmare," said a current FDA official who requested anonymity because they were not authorized to speak to the press. "Things that used to function are no longer functioning." The big picture: The FDA not only reviews drugs for safety and efficacy but acts as a nerve center churning out information in real time when there are adverse events, quality problems or drug shortages. - But in several recent instances, current and former officials said, databases didn't get updated promptly or were missing key information because there were no employees to maintain them.
- The FDA has previously referred all questions to HHS, which didn't respond to requests for comment.
Zoom in: The FDA's drug database, which is updated when new drugs are approved, get labeling changes or are pulled from the market, has a growing amount of missing information, an FDA official who was laid off told Axios. - Most entries into this database since the sweeping April 1 job cuts are missing labeling information, which tells doctors what the drug is approved for, what it shouldn't be used for, dosing instructions and side effects.
- Other repositories with delayed updates due to staff cuts are the National Drug Code Directory and the Drug Registration and Listing Database — which wasn't updated for several days until a few laid-off employees returned part time to help.
- Their jobs are still set to be eliminated on June 2.
"Once June happens ... we have no idea what the plans are," the official said. Go deeper
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